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Nerve, muscle, and inflammatory cells involved in gastrointestinal (GI) function have high-energy requirements and are affected in mitochondrial defect. Mitochondria are cytoplasmic organelles that produce the bulk of the ATP for cellular energy needs.
Given the important role of mitochondria in neuromuscular function and inflammation that has explored new scientific focusing. They are associated with IBS, functional constipation, functional diarrhea, chronic abdominal pain, and functional dyspepsia.
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